Nanphenylos (Nandrolone Phenylpropionate)

About the Product

Nanphenylos is a research compound from Driada Medical, presented as a solution for intramuscular injection containing Nandrolone Phenylpropionate. Nandrolone Phenylpropionate is a synthetic anabolic androgenic steroid (AAS) derived from testosterone, with a modification that reduces its androgenic potency while enhancing its anabolic properties. It is a 19-nortestosterone derivative, lacking the carbon atom at position 19, which gives it a distinct pharmacological profile. The phenylpropionate ester provides a medium duration of action, offering a faster onset and shorter half-life compared to the decanoate ester, making it suitable for research protocols requiring more rapid pharmacokinetics.

The product is intended for laboratory research use only and features an integrated QR code on the packaging for detailed product verification.

• Product Name: Nanphenylos (Nandrolone Phenylpropionate)

• Brand: Driada Medical

• Form: Injectable solution (oil-based)

• For Research Use Only.

Research Applications & Mechanism of Action

• 19-Nortestosterone Derivative: Nandrolone is a derivative of testosterone with the carbon atom at position 19 removed. This structural modification results in:

  • Reduced androgenic potency compared to testosterone.

  • Enhanced anabolic-to-androgenic ratio.

  • Reduced 5α-reduction to active metabolites.

  • Distinct receptor binding profile.

• Androgen Receptor Agonist: Nandrolone Phenylpropionate functions as an agonist at the androgen receptor (AR). Upon administration, the phenylpropionate ester is cleaved by esterases, releasing active nandrolone which binds to ARs in target tissues. This binding initiates a signaling cascade that regulates gene transcription via hormone response elements (HREs), mediating anabolic and androgenic effects.

• Medium-Acting Ester Profile: The phenylpropionate ester provides a medium duration of action, offering researchers:

  • Faster onset compared to longer-acting esters (decanoate).

  • Shorter half-life for more controlled dosing schedules.

  • Flexibility in study design requiring more rapid pharmacokinetics.

• Aromatization Profile: Nandrolone undergoes limited aromatization to estrogen (estradiol), with approximately 20% of the aromatization rate of testosterone. This provides researchers with a compound that has:

  • Minimal estrogenic effects compared to testosterone.

  • A unique balance of androgenic and estrogenic activity.

• 5α-Reduction Profile: Nandrolone is reduced by 5α-reductase to dihydronandrolone, which has reduced androgenic potency compared to the parent compound. This is in contrast to testosterone, which is converted to the more potent dihydrotestosterone (DHT). This unique profile allows researchers to study:

  • Tissue-specific effects of nandrolone.

  • Differences in 5α-reduction pathways between androgens.

• Protein Anabolism: Nandrolone promotes protein anabolism (building up of proteins) and reduces protein catabolism (breakdown), which can be studied in models of muscle physiology, bone metabolism, and metabolic research.

• Metabolic Research: Studies can include investigating effects on:

  • Lipid metabolism and adipocyte function.

  • Glucose metabolism and insulin sensitivity.

  • Nitrogen retention and protein synthesis.

  • Bone metabolism and calcium homeostasis.

Research & Scientific Background

• Chemical Background: Nandrolone (19-nortestosterone) was first synthesized in the 1950s and has been extensively studied for its anabolic properties. The phenylpropionate ester provides a medium duration of action, positioned between the short-acting propionate and the long-acting decanoate esters.

• Comparison with Other Esters: Nandrolone Phenylpropionate offers a distinct pharmacokinetic profile compared to other nandrolone esters:

  • Faster onset than Nandrolone Decanoate.

  • Shorter half-life allowing for more frequent dosing.

  • Medium duration providing flexibility in research protocols.

  • Useful for comparative studies on ester chain length effects.

• Clinical Context: Nandrolone Phenylpropionate has been studied in clinical research contexts, particularly in relation to:

  • Treatment of anemia and stimulation of erythropoiesis.

  • Management of osteoporosis and bone density research.

  • Wasting syndromes and cachexia research.

  • Hormone replacement therapy research.

• Anabolic-to-Androgenic Ratio Research: Nandrolone's favorable anabolic-to-androgenic ratio makes it a valuable tool for studying:

  • Separation of anabolic and androgenic effects.

  • Mechanisms of anabolic action.

  • Tissue-specific effects of androgens.

• Aromatase Research: The limited aromatization of nandrolone allows researchers to study:

  • Effects of androgens with minimal estrogenic activity.

  • Comparative effects of aromatizable and non-aromatizable compounds.

  • Role of estrogen in androgen-mediated effects.

• 5α-Reductase Research: The unique 5α-reduction profile of nandrolone makes it a valuable tool for studying:

  • Role of 5α-reductase in androgen action.

  • Tissue-specific effects of 5α-reduced metabolites.

  • Comparative effects of 5α-reduced and non-5α-reduced compounds.

• Muscle Physiology Research:

  • Skeletal Muscle Studies: Investigating the effects of nandrolone on muscle protein synthesis, satellite cell activation, and muscle fiber type composition.

  • Myogenic Differentiation: Studying the role of androgens in muscle cell differentiation and development.

• Bone Metabolism Research:

  • Osteoblast Studies: Investigating the effects on bone formation and mineralization.

  • Osteoporosis Research: Studying the potential benefits of nandrolone in bone density maintenance.

• Erythropoiesis Research:

  • Red Blood Cell Production: Studying the stimulatory effects on erythropoiesis and hemoglobin synthesis.

  • Anemia Research: Investigating potential therapeutic applications.

• Endocrinology Research:

  • Hypothalamic-Pituitary-Gonadal Axis: Studying the suppression of gonadotropins and the feedback mechanisms of androgens.

  • Hormonal Regulation: Investigating the interplay between nandrolone and other hormones.

• Comparative Ester Studies: The availability of both phenylpropionate and decanoate esters of nandrolone allows for comparative research on:

  • Ester chain length effects on release kinetics.

  • Pharmacokinetic profiles of different ester formulations.

  • Dosing frequency optimization in research protocols.