BPC-157

About the Product

Genetic Labs BPC-157 is a high-purity synthetic peptide (research grade) supplied in a vial containing 10mg of lyophilized (freeze-dried) powder. BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids, derived from a protective protein found in human gastric juice. It is a stable peptide that has been extensively studied for its remarkable cytoprotective, regenerative, and anti-inflammatory properties. BPC-157 promotes healing and repair across multiple tissue types through its ability to stimulate angiogenesis, modulate growth factor expression, and protect cells from damage. This makes it a versatile research tool in wound healing, gastroenterology, orthopedics, and neurobiology.

Kit Contents:

• 1 Vial with 10mg BPC-157 (Lyophilized Powder)

• 1 Vial with 3mL Bacteriostatic Water (Diluent)

For Laboratory Research Use Only. Not for human consumption.

Benefits (Research Scope)

• Cytoprotective Pentadecapeptide: BPC-157 is a stable synthetic peptide that exhibits potent cytoprotective, regenerative, and anti-inflammatory properties. It promotes the healing of various tissues, including gastrointestinal tract, muscle, tendon, ligament, bone, and neural tissue, through multiple synergistic mechanisms.

• Versatile Research Tool: Suitable for a wide range of studies, including:

  • Gastrointestinal Research: Studies on gastric ulcers, inflammatory bowel disease (IBD), leaky gut syndrome, and intestinal barrier integrity.

  • Wound Healing & Tissue Repair: Research into accelerated wound closure, angiogenesis, extracellular matrix remodeling, and tissue regeneration.

  • Muscle & Tendon Research: Studies on muscle healing, tendon repair, ligament regeneration, and sports injury models.

  • Anti-Inflammatory Research: Investigation into the modulation of inflammatory cytokines and the promotion of anti-inflammatory microenvironments.

  • Neuroprotection: Research into neural repair, axonal growth, neuroinflammation modulation, and neuroprotection in models of neurological injury.

  • Bone & Cartilage Research: Studies on bone healing, fracture repair, and cartilage regeneration.

  • Organ Protection: Investigation into the protective effects against toxic and ischemic damage in liver, kidney, and other organs.

  • Dental Research: Studies on periodontal healing and oral tissue repair.

• Practical Formulation: The lyophilized powder ensures stability and extended shelf life, while the included bacteriostatic water facilitates easy reconstitution for both in vitro and in vivo experiments.

Research & Science

BPC-157 is one of the most extensively studied regenerative peptides, with a robust body of preclinical research spanning several decades and covering a wide range of tissue repair applications.

• Mechanism of Action: BPC-157 exerts its biological effects through multiple interrelated mechanisms:

  • Angiogenesis Promotion: BPC-157 stimulates the formation of new blood vessels through upregulation of vascular endothelial growth factor (VEGF) and other angiogenic factors, improving blood supply to damaged tissues.

  • Growth Factor Modulation: Enhances the expression of growth factors, including VEGF, FGF (fibroblast growth factor), and TGF-β (transforming growth factor-beta), which are essential for tissue repair and regeneration.

  • Collagen Synthesis: Promotes collagen production and deposition, essential for wound healing and tissue integrity.

  • Anti-Inflammatory Effects: Reduces the production of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6) and promotes a regenerative, anti-inflammatory cellular environment.

  • Nitric Oxide Modulation: BPC-157 modulates nitric oxide (NO) production, which plays a critical role in angiogenesis, vasodilation, and tissue repair.

  • Cell Survival & Protection: Protects cells from oxidative stress, toxic damage, and apoptosis through activation of survival signaling pathways.

  • Gastrointestinal Protection: BPC-157 promotes the healing of gastric and intestinal mucosa through increased mucus production, enhanced cell proliferation, and protection from acid and other irritants.

• Gastrointestinal Research: BPC-157 has demonstrated remarkable efficacy in gastrointestinal research:

  • Gastric Ulcer Healing: Accelerates healing of various types of gastric ulcers (stress-induced, alcohol-induced, NSAID-induced).

  • Inflammatory Bowel Disease (IBD): Reduces inflammation and promotes healing in models of colitis and Crohn's disease.

  • Intestinal Barrier Integrity: Protects and restores intestinal barrier function in models of leaky gut syndrome.

  • Organ Protection: Protects the liver, kidney, and pancreas from toxic and ischemic damage.

• Muscle, Tendon & Ligament Research: BPC-157 has been extensively studied for its effects on the musculoskeletal system:

  • Muscle Healing: Accelerates recovery from muscle injury and damage.

  • Tendon Repair: Promotes healing of tendon tears and tendinopathy with improved collagen organization and tensile strength.

  • Ligament Healing: Enhances ligament repair and recovery.

  • Sports Injury Models: Demonstrates accelerated recovery and return to function in various injury models.

• Neuroprotective Research: BPC-157 has demonstrated significant neuroprotective properties:

  • Promotes neuronal survival and axonal growth.

  • Protects against neurotoxicity and apoptosis.

  • Modulates neuroinflammation .

  • Promotes recovery in models of spinal cord injury, traumatic brain injury, and peripheral nerve injury.

• Bone & Cartilage Research: BPC-157 promotes:

  • Bone healing: Accelerates fracture repair with improved bone formation.

  • Cartilage regeneration: Promotes repair of damaged cartilage.

• Anti-Inflammatory Research: BPC-157's potent anti-inflammatory effects make it valuable for studying inflammatory conditions, including arthritis, inflammatory bowel disease, and other inflammatory disorders.

• Angiogenesis Research: The peptide's ability to stimulate new blood vessel formation makes it a valuable tool for studying angiogenesis-related processes in wound healing and tissue regeneration.

• Focus on Genetic Variability: Research is exploring how genetic polymorphisms in growth factor genes, inflammatory pathway genes, and tissue repair-related genes may influence individual responses to BPC-157, providing insights for personalized regenerative medicine approaches.