A black box of Generic Tesamorelin 5 MG for laboratory research reagents, displayed on a white lab bench with pipettes, centrifuges, and other lab equipment in the blurred background.

Tesamorelin

€44,00
€44,00
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A black box of Generic Tesamorelin 5 MG for laboratory research reagents, displayed on a white lab bench with pipettes, centrifuges, and other lab equipment in the blurred background.
  • A black box of Generic Tesamorelin 5 MG for laboratory research reagents, displayed on a white lab bench with pipettes, centrifuges, and other lab equipment in the blurred background.
  • A black box of Generic Tesamorelin 5 MG for laboratory research reagents, displayed on a white lab bench with pipettes, centrifuges, and other lab equipment in the blurred background.
Tesamorelin

Tesamorelin

€44,00
€44,00

About the Product

Genetic Labs Tesamorelin is a high-purity synthetic peptide (research grade) supplied in a vial containing 5mg of lyophilized (freeze-dried) powder. Tesamorelin is a growth hormone-releasing hormone (GHRH) analog, specifically a stabilized synthetic peptide comprising 44 amino acids. It functions as a potent secretagogue, stimulating the pituitary gland to release endogenous growth hormone (GH).

Kit Contents:

  • 1 Vial with 5mg Tesamorelin (Lyophilized Powder)

  • 1 Vial with Bacteriostatic Water (Diluent)

For Laboratory Research Use Only. Not for human consumption.

Benefits (Research Scope)

  • GHRH Analog: As a synthetic analog of growth hormone-releasing hormone, Tesamorelin binds to GHRH receptors on pituitary somatotroph cells, stimulating the natural pulsatile release of growth hormone, closely mimicking the body's physiological rhythm.

  • Versatile Research Tool: Suitable for a wide range of studies, including:

    • Endocrinology & Metabolism: Research into growth hormone deficiency, age-related GH decline, and metabolic disorders such as lipodystrophy and visceral adiposity.

    • Neuroendocrinology: Studies on the hypothalamic-pituitary axis, neuroprotection, and cognitive function.

    • Body Composition: Investigation into fat redistribution, particularly reduction of visceral adipose tissue (VAT), and lean body mass preservation.

    • Aging Research: Studies on the role of GH in age-related physiological changes, including sarcopenia, bone density, and skin health.

  • Practical Formulation: The lyophilized powder ensures stability and extended shelf life, while the included bacteriostatic water facilitates easy reconstitution for both in vitro and in vivo experiments.

Research & Science

Tesamorelin is a well-characterized peptide with a strong body of preclinical and clinical research supporting its mechanism and applications.

  • Mechanism of Action: Tesamorelin is a synthetic 44-amino-acid peptide analog of human GHRH. It binds to the GHRH receptor (GHRH-R) on somatotroph cells in the anterior pituitary, activating the cAMP signaling pathway and stimulating the synthesis and release of growth hormone. This, in turn, elevates circulating levels of insulin-like growth factor-1 (IGF-1), mediating many of the anabolic and metabolic effects.

  • Clinical Validation: Tesamorelin has been extensively studied in clinical trials, most notably for the treatment of HIV-associated lipodystrophy, where it was shown to significantly reduce visceral adipose tissue (VAT) and improve lipid profiles without adversely affecting glucose metabolism.

  • Neuroendocrine Research: Current research is exploring Tesamorelin's potential in neurodegenerative conditions. GH and IGF-1 have demonstrated neuroprotective properties, and Tesamorelin's ability to elevate these hormones makes it a candidate for studying cognitive decline, traumatic brain injury (TBI), and other neurological disorders.

  • Focus on Genetic Variability: Ongoing research is investigating how genetic polymorphisms in the GHRH receptor, GH1 gene, or related pathways may influence individual responses to GHRH analogs, opening avenues for personalized therapeutic strategies in GH deficiency and metabolic disorders.

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