{"product_id":"tb-500","title":"TB-500","description":"\u003ch4\u003e\u003cspan class=\"\"\u003eAbout the Product\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eGenetic Labs TB-500\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e is a high-purity synthetic peptide (research grade) supplied in a vial containing 10mg of lyophilized (freeze-dried) powder. TB-500 is a synthetic version of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid peptide found in virtually all human cells. It is a potent actin-binding peptide that plays a crucial role in cell migration, proliferation, and differentiation. The synthetic variant, TB-500, is specifically engineered to enhance the regenerative and reparative properties of the native peptide for research applications.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eKit Contents:\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003e1 Vial with 10mg TB-500 (Lyophilized Powder)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003e1 Vial with 3mL Bacteriostatic Water (Diluent)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eFor Laboratory Research Use Only. Not for human consumption.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch4\u003e\u003cspan class=\"\"\u003eBenefits (Research Scope)\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eActin-Binding Peptide:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e TB-500 binds to actin, a key protein in the cytoskeleton, promoting cell migration, adhesion, and survival. This makes it a valuable tool for studying wound healing, tissue regeneration, and cellular repair mechanisms.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eVersatile Research Tool:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Suitable for a wide range of studies, including:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eWound Healing \u0026amp; Tissue Repair:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Research into accelerated wound closure, angiogenesis (new blood vessel formation), and extracellular matrix remodeling.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eMuscle \u0026amp; Tendon Regeneration:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Studies on skeletal muscle, cardiac muscle, and tendon repair following injury or degenerative conditions.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eNeuroprotection:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Investigation into neural repair, axonal growth, and neuroinflammation modulation following spinal cord injury or neurodegenerative models.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eAnti-Inflammatory Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Studies on the regulation of inflammatory cytokines and the promotion of an anti-inflammatory microenvironment.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eCardiovascular Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Research into cardiac repair following myocardial infarction (heart attack), promoting survival of cardiomyocytes and reducing scar tissue formation.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003ePractical Formulation:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e The lyophilized powder ensures stability and extended shelf life, while the included bacteriostatic water facilitates easy reconstitution for both \u003c\/span\u003e\u003cem\u003e\u003cspan class=\"\"\u003ein vitro\u003c\/span\u003e\u003c\/em\u003e\u003cspan class=\"\"\u003e and \u003c\/span\u003e\u003cem\u003e\u003cspan class=\"\"\u003ein vivo\u003c\/span\u003e\u003c\/em\u003e\u003cspan class=\"\"\u003e experiments.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch4\u003e\u003cspan class=\"\"\u003eResearch \u0026amp; Science\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eTB-500 (Thymosin Beta-4) is one of the most extensively studied regenerative peptides, with a wealth of preclinical research supporting its multiple biological functions.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eMechanism of Action:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e TB-500 binds to monomeric actin (G-actin), sequestering it and regulating actin polymerization dynamics. This interaction controls cell motility, cytoskeletal reorganization, and cell survival pathways. Additionally, TB-500 modulates inflammatory responses by downregulating pro-inflammatory cytokines (such as TNF-α and IL-1β) and upregulating anti-inflammatory mediators, while also promoting angiogenesis through upregulation of vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eRegenerative Properties:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Research has demonstrated that TB-500 promotes the proliferation and migration of endothelial cells, keratinocytes, and fibroblasts to wound sites, accelerating tissue repair. It also plays a role in promoting hair follicle stem cell activation and hair growth in research models.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eCardioprotective Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Studies have shown that TB-500 improves cardiac function, reduces scar tissue, and enhances vascularization in animal models of myocardial infarction, making it a promising compound for cardiovascular repair research.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eMusculoskeletal Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e TB-500 has been investigated for its ability to improve healing of muscle tears, tendon injuries, and ligament damage, with studies showing improved collagen deposition, reduced scar tissue, and enhanced functional recovery.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eNeuroregenerative Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Emerging research explores TB-500's role in promoting neurite outgrowth, protecting against excitotoxicity, and modulating inflammation in models of stroke, traumatic brain injury, and spinal cord injury.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eFocus on Genetic Variability:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Current research is exploring how genetic factors, such as polymorphisms in actin-related genes or inflammatory pathway genes, may influence individual responses to TB-500, paving the way for personalized regenerative medicine approaches.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Genetic Labs","offers":[{"title":"Default Title","offer_id":58672453583173,"sku":null,"price":42.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1077\/7614\/7781\/files\/GeneticLabs-TB-500_10mg.jpg?v=1784936294","url":"https:\/\/genetic-peps.shop\/products\/tb-500","provider":"Genetic Peps","version":"1.0","type":"link"}