{"product_id":"ss-31","title":"SS-31","description":"\u003ch4\u003e\u003cspan class=\"\"\u003eAbout the Product\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eGenetic Labs SS-31\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e is a high-purity synthetic peptide (research grade) supplied in a vial containing 10mg of lyophilized (freeze-dried) powder. SS-31, also known as \u003c\/span\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eElamipretide\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e, is a novel mitochondrial-targeted peptide composed of alternating aromatic and basic amino acids (D-Arg-dimethylTyr-Lys-Phe-NH2). Its unique structure allows it to selectively accumulate in the inner mitochondrial membrane, where it exerts potent protective effects against oxidative stress and mitochondrial dysfunction.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eKit Contents:\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003e1 Vial with 10mg SS-31 (Lyophilized Powder)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003e1 Vial with 3mL Bacteriostatic Water (Diluent)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eFor Laboratory Research Use Only. Not for human consumption.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch4\u003e\u003cspan class=\"\"\u003eBenefits (Research Scope)\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eMitochondrial-Targeted Peptide:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e SS-31 specifically targets the inner mitochondrial membrane, where it interacts with cardiolipin, a phospholipid essential for mitochondrial structure and function. This interaction stabilizes the mitochondrial membrane, prevents the formation of reactive oxygen species (ROS), and supports efficient energy (ATP) production.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eVersatile Research Tool:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Suitable for a wide range of studies, including:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eMitochondrial Dysfunction:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Research into aging-related mitochondrial decline, mitochondrial diseases, and disorders involving impaired energy metabolism.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eCardiovascular Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Studies on cardiac ischemia-reperfusion injury, heart failure, and cardiomyopathy, where mitochondrial damage plays a key role.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eNeurodegenerative Disorders:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Investigation into Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis (ALS), all of which involve mitochondrial dysfunction.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eRenal Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Studies on acute kidney injury, chronic kidney disease, and contrast-induced nephropathy.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eMetabolic Disorders:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Research into insulin resistance, obesity, and type 2 diabetes, where mitochondrial dysfunction contributes to disease progression.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eSkeletal Muscle Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Studies on sarcopenia, muscular dystrophy, and age-related muscle weakness.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003ePractical Formulation:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e The lyophilized powder ensures stability and extended shelf life, while the included bacteriostatic water facilitates easy reconstitution for both \u003c\/span\u003e\u003cem\u003e\u003cspan class=\"\"\u003ein vitro\u003c\/span\u003e\u003c\/em\u003e\u003cspan class=\"\"\u003e and \u003c\/span\u003e\u003cem\u003e\u003cspan class=\"\"\u003ein vivo\u003c\/span\u003e\u003c\/em\u003e\u003cspan class=\"\"\u003e experiments.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch4\u003e\u003cspan class=\"\"\u003eResearch \u0026amp; Science\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eSS-31 (Elamipretide) is one of the most extensively studied mitochondrial-targeted therapeutic peptides, with a robust body of preclinical and clinical research supporting its mechanism and broad therapeutic potential.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eMechanism of Action:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e SS-31 is a cationic, aromatic peptide that binds selectively to cardiolipin in the inner mitochondrial membrane. This binding:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eStabilizes the mitochondrial membrane structure\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e and prevents the disruption of cristae architecture.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eInhibits the formation of reactive oxygen species (ROS)\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e without interfering with beneficial mitochondrial signaling.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eRestores mitochondrial bioenergetics\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e by facilitating the transfer of electrons between complexes III and IV of the electron transport chain.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003ePrevents cytochrome c release\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e and downstream apoptosis pathways.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eClinical Validation:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e SS-31 has advanced into multiple clinical trials for various indications, including:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eHeart Failure:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Demonstrated improvements in cardiac function and reduced biomarkers of cardiac stress.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eBarth Syndrome:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Showed improvements in exercise capacity and cardiac function in this rare mitochondrial disorder.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eLeber's Hereditary Optic Neuropathy (LHON):\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Evaluated for visual function improvement in mitochondrial optic neuropathy.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eAge-Related Macular Degeneration (AMD):\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Investigated for its potential to protect retinal cells from oxidative damage.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eNeuroprotective Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Studies have demonstrated that SS-31 significantly reduces neuronal cell death, preserves mitochondrial function, and improves cognitive outcomes in animal models of neurodegenerative diseases.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eRenoprotective Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e SS-31 has shown efficacy in reducing oxidative damage and preserving renal function in models of acute kidney injury and diabetic nephropathy.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eAging \u0026amp; Longevity Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e As mitochondrial dysfunction is a hallmark of aging, SS-31 is being investigated as a potential therapeutic to counteract age-related decline in cellular energy production, muscle function, and metabolic health.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eFocus on Genetic Variability:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Current research is exploring how genetic variations in mitochondrial DNA (mtDNA) and nuclear genes involved in mitochondrial function may influence individual responses to SS-31, paving the way for personalized mitochondrial medicine.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Genetic Labs","offers":[{"title":"Default Title","offer_id":58672475078981,"sku":null,"price":56.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1077\/7614\/7781\/files\/GeneticLabs-SS-31_10mg.jpg?v=1784936395","url":"https:\/\/genetic-peps.shop\/products\/ss-31","provider":"Genetic Peps","version":"1.0","type":"link"}