{"product_id":"liothymed-triiodothyronine","title":"Liothymed (Triiodothyronine)","description":"\u003ch4\u003e\u003cspan class=\"\"\u003eAbout the Product\u003c\/span\u003e\u003c\/h4\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eLiothymed\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e is a research compound from Driada Medical, containing \u003c\/span\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eTriiodothyronine (T3)\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e , specifically the active form \u003c\/span\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eL-liothyronine\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e \u003c\/span\u003e\u003ca href=\"https:\/\/tc.iccri.net\/2026\/02\/10\/liothymed-25-mcg-un-allie-pour-la-musculation\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/thela.africa\/2026\/06\/24\/como-tomar-liothymed-25-mcg-driada-medical-guia-completa\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. T3 is one of the two major hormones produced by the thyroid gland and is the biologically active form of thyroid hormone, responsible for the vast majority of the physiological effects attributed to thyroid function \u003c\/span\u003e\u003ca href=\"https:\/\/https-pubmed-ncbi-nlm-nih-gov-443.webvpn.ynu.edu.cn\/39579306\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12346460\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/a-2698-0521\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eThe compound is a synthetic version of endogenous T3, a 3,5,3′-triiodothyronine molecule with the molecular formula C₁₅H₁₂I₃NO₄ and a molecular weight of approximately 651 g\/mol \u003c\/span\u003e\u003ca href=\"https:\/\/www.scbt.com\/p\/3-3prime-5-triiodo-d-thyronine-5714-08-9?srsltid=AfmBOoqQ4PUsI_vXrtBeLMjhP-mYJwzFe1QQozannFUEA8jRkDYO9dHt\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. It functions by binding to nuclear thyroid hormone receptors (TRs), acting as a ligand-dependent transcription factor that regulates the expression of genes involved in metabolism, growth, and development \u003c\/span\u003e\u003ca href=\"https:\/\/https-pubmed-ncbi-nlm-nih-gov-443.webvpn.ynu.edu.cn\/39579306\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eThe product is intended for \u003c\/span\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003elaboratory research use only\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e and features an integrated QR code on the packaging for detailed product verification.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eProduct Name:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Liothymed (Triiodothyronine \/ L-Liothyronine)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eBrand:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Driada Medical\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eForm:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Solution for research applications\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eCAS Number:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e 6893-02-3 (L-T3) \u003c\/span\u003e\u003ca href=\"https:\/\/www.scbt.com\/p\/3-3prime-5-triiodo-d-thyronine-5714-08-9?srsltid=AfmBOoqQ4PUsI_vXrtBeLMjhP-mYJwzFe1QQozannFUEA8jRkDYO9dHt\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eFor Research Use Only.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch4\u003e\u003cspan class=\"\"\u003eResearch Applications \u0026amp; Mechanism of Action\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eNuclear Thyroid Hormone Receptor Agonist:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Triiodothyronine functions as a potent agonist at nuclear thyroid hormone receptors (TRα and TRβ) \u003c\/span\u003e\u003ca href=\"https:\/\/https-pubmed-ncbi-nlm-nih-gov-443.webvpn.ynu.edu.cn\/39579306\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. Upon binding to these receptors, the T3-TR complex translocates to the nucleus, binds to thyroid hormone response elements (TREs) on DNA, and recruits coactivators or corepressors to modulate the transcription of target genes \u003c\/span\u003e\u003ca href=\"https:\/\/https-pubmed-ncbi-nlm-nih-gov-443.webvpn.ynu.edu.cn\/39579306\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. This genomic action regulates a wide array of physiological processes, including basal metabolic rate, thermogenesis, and mitochondrial biogenesis \u003c\/span\u003e\u003ca href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/a-2698-0521\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eMetabolic Rate \u0026amp; Energy Homeostasis Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e T3 is a master regulator of metabolic rate and energy expenditure. Research applications include studying its effects on mitochondrial function, oxidative phosphorylation, and whole-body metabolism \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/a-2698-0521\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. Studies have shown that T3 treatment enhances mitochondrial respiration and autophagy, making it a key compound for metabolic research \u003c\/span\u003e\u003ca href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/a-2698-0521\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eLipolysis \u0026amp; Lipid Metabolism Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e T3 promotes lipolysis (fat breakdown) and fatty acid oxidation, making it relevant for studies on adipocyte function, lipid metabolism, and body composition \u003c\/span\u003e\u003ca href=\"https:\/\/eatonarabia.com\/liothymed-25-mcg-%ce%b1%ce%be%ce%b9%ce%bf%ce%bb%cf%8c%ce%b3%ce%b7%cf%83%ce%b7-%ce%ba%ce%b1%ce%b9-%cf%87%cf%81%ce%ae%cf%83%ce%b7\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/tc.iccri.net\/2026\/02\/10\/liothymed-25-mcg-un-allie-pour-la-musculation\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/thela.africa\/2026\/06\/24\/como-tomar-liothymed-25-mcg-driada-medical-guia-completa\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eCardiovascular \u0026amp; Neurological Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e T3 is essential for normal cardiac function and cognitive performance. Research uses include investigating T3's effects on cardiac contractility, heart rate, and neurocognitive function, as well as its interaction with the hypothalamic-pituitary-thyroid (HPT) axis \u003c\/span\u003e\u003ca href=\"https:\/\/eatonarabia.com\/liothymed-25-mcg-%ce%b1%ce%be%ce%b9%ce%bf%ce%bb%cf%8c%ce%b3%ce%b7%cf%83%ce%b7-%ce%ba%ce%b1%ce%b9-%cf%87%cf%81%ce%ae%cf%83%ce%b7\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eAging \u0026amp; Longevity Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Recent research has highlighted T3's role in modulating aging pathways, including mechanistic target of rapamycin (mTOR), AMPK, IGF-1, sirtuins, and FOXO transcription factors. Studies have explored how subclinical variations in T3 levels may affect healthspan, cognitive preservation, and mitochondrial integrity, providing avenues for research into healthy aging and metabolic resilience \u003c\/span\u003e\u003ca href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/a-2698-0521\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eDrug Metabolism \u0026amp; Pharmacogenomics Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Emerging research has identified genetic polymorphisms in deiodinase enzymes (e.g., \u003c\/span\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eDIO2 Thr92Ala\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e) that may affect the peripheral conversion of T4 to T3 \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. This has led to research exploring how genetic factors influence individual responses to thyroid hormones and the potential for personalized endocrine optimization \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003e\u003cspan class=\"\"\u003eResearch \u0026amp; Scientific Background\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003ePhysiological Context:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e The thyroid gland primarily secretes thyroxine (T4), a prohormone that must be converted in peripheral tissues into the active form, T3, via deiodinase enzymes (DIO1, DIO2) \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. T3 binds to thyroid hormone receptors with significantly higher affinity than T4 and mediates the majority of thyroid hormone action \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. Normal serum T3 levels are tightly regulated by the HPT axis, with TSH serving as the primary feedback signal.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003ePharmacokinetics:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Synthetic L-liothyronine (T3) has a rapid onset of action and a relatively short half-life (approximately 24 hours) compared to T4 \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. It is absorbed quickly and, due to its short duration, can cause fluctuations in serum T3 levels throughout the day in research models \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. These pharmacokinetic properties make T3 a valuable tool for studying acute thyroid hormone effects but also require careful dosing and monitoring in long-term experiments \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/thela.africa\/2026\/06\/24\/como-tomar-liothymed-25-mcg-driada-medical-guia-completa\/\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eT3 vs. T4 Research:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e While T4 monotherapy is the clinical standard for hypothyroidism, a subset of patients continue to experience symptoms despite normalized TSH levels \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. Research is exploring the physiological distinctions between T4 and T3, including the tissue-specific roles of deiodinase enzymes and the potential benefits of T3-containing therapies in certain research models \u003c\/span\u003e\u003ca href=\"https:\/\/dev.europepmc.org\/article\/MED\/40851876#free-full-text\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"ds-markdown-paragraph\"\u003e\u003cstrong\u003e\u003cspan class=\"\"\u003eThyroid Hormone \u0026amp; Aging:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan class=\"\"\u003e Recent mechanistic studies have begun to characterize the relationship between T3, cellular metabolism, and longevity \u003c\/span\u003e\u003ca href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/a-2698-0521\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. T3 is a key modulator of metabolic flexibility and mitochondrial health, and altered thyroid function has been paradoxically associated with increased longevity in some populations \u003c\/span\u003e\u003ca href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/a-2698-0521\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e. This line of research is exploring how thyroid hormone levels affect pathways such as mTOR, AMPK, and mitochondrial biogenesis, which are central to aging biology \u003c\/span\u003e\u003ca href=\"https:\/\/www.thieme-connect.de\/products\/ejournals\/abstract\/10.1055\/a-2698-0521\" rel=\"noreferrer\" style=\"cursor: default;\" target=\"_blank\"\u003e\u003c\/a\u003e\u003cspan class=\"\"\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Driada","offers":[{"title":"Default Title","offer_id":58726479429957,"sku":null,"price":30.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1077\/7614\/7781\/files\/Driada-Liothymed.jpg?v=1785450369","url":"https:\/\/genetic-peps.shop\/products\/liothymed-triiodothyronine","provider":"Genetic Peps","version":"1.0","type":"link"}