An open clear plastic HGH kit box containing several small labeled vials, with a white sign inside reading 'Genetic Labs HGH KIT 100 uLs + 10 ML BAC WATER.' The box sits on a lab bench with pipettes, a digital magnetic stirrer, and other lab equipment blurred in the background.

HGH Kit

€184,00
€184,00
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An open clear plastic HGH kit box containing several small labeled vials, with a white sign inside reading 'Genetic Labs HGH KIT 100 uLs + 10 ML BAC WATER.' The box sits on a lab bench with pipettes, a digital magnetic stirrer, and other lab equipment blurred in the background.
  • An open clear plastic HGH kit box containing several small labeled vials, with a white sign inside reading 'Genetic Labs HGH KIT 100 uLs + 10 ML BAC WATER.' The box sits on a lab bench with pipettes, a digital magnetic stirrer, and other lab equipment blurred in the background.
  • An open clear plastic HGH kit box containing several small labeled vials, with a white sign inside reading 'Genetic Labs HGH KIT 100 uLs + 10 ML BAC WATER.' The box sits on a lab bench with pipettes, a digital magnetic stirrer, and other lab equipment blurred in the background.
HGH Kit

HGH Kit

€184,00
€184,00

About the Product

Genetic Labs HGH Kit is a high-purity research-grade somatropin (recombinant human growth hormone, rHGH) kit supplied with 100iu of lyophilized growth hormone and 10mL of bacteriostatic water for reconstitution. With a purity level of 99.8%, this kit provides researchers with a highly purified form of the 191-amino-acid peptide hormone that is identical to endogenous human growth hormone (GH) produced by the pituitary gland. HGH plays a fundamental role in growth, cellular regeneration, metabolism, and overall physiological homeostasis, making it a cornerstone research tool in endocrinology, metabolism, and aging studies.

Kit Contents:

  • 10 Vials × 10iu Human Growth Hormone (Lyophilized Powder) – Total 100iu

  • 1 Vial × 10mL Bacteriostatic Water (Diluent)

Purity: >99.8%

For Laboratory Research Use Only. Not for human consumption.

Storage: Store at 2-8°C (refrigerated). Do not freeze. Protect from light.

Benefits (Research Scope)

  • Recombinant Human Growth Hormone (rHGH): This product contains biosynthetic somatropin, a 191-amino-acid peptide identical to endogenous human growth hormone. It acts as a potent agonist at the growth hormone receptor (GHR), stimulating growth, cellular regeneration, and metabolic processes. The 99.8% purity ensures minimal contamination and reliable, reproducible research results.

  • Versatile Research Tool: Suitable for a wide range of studies, including:

    • Endocrinology: Research into growth hormone regulation, the hypothalamic-pituitary-somatotropic axis, growth hormone deficiency, and acromegaly.

    • Metabolic Disorders: Studies on glucose metabolism, lipid metabolism, insulin sensitivity, and obesity.

    • Muscle Physiology: Research into muscle growth, protein synthesis, muscle wasting conditions (sarcopenia, cachexia), and recovery.

    • Bone & Cartilage Research: Studies on bone formation, bone mineral density, growth plate biology, and osteoporosis.

    • Aging Research: Investigation into age-related decline in GH and IGF-1 levels, cellular senescence, and interventions to promote healthy aging.

    • Tissue Regeneration: Research into wound healing, tissue repair, and organ regeneration.

    • Neurobiology: Studies on neuroprotection, cognitive function, and neuroregeneration.

    • Cancer Research: Investigation into GH/IGF-1 signaling in tumor growth and proliferation.

    • Stem Cell Research: Studies on stem cell proliferation and differentiation.

  • Practical Kit Format: The kit includes multiple vials (10 × 10iu), allowing for flexible experimental design and reduced risk of contamination from repeated vial use. The included 10mL bacteriostatic water facilitates easy reconstitution with preservative properties for extended use.

Research & Science

Human Growth Hormone (somatropin) is one of the most extensively studied peptide hormones in biomedical research, with a rich history of scientific investigation and a robust body of literature.

  • Mechanism of Action: HGH exerts its biological effects through two primary mechanisms:

    • Direct Effects: Binding to the growth hormone receptor (GHR) on target cells, activating the JAK2/STAT5 signaling pathway, which regulates gene expression involved in growth, metabolism, and cell survival.

    • Indirect Effects (IGF-1 Mediated): Stimulating the liver and peripheral tissues to produce insulin-like growth factor-1 (IGF-1), which mediates many of the anabolic and growth-promoting effects of GH through activation of the IGF-1 receptor (IGF-1R) and downstream PI3K/Akt and MAPK/ERK pathways.

  • Metabolic Effects: HGH has profound effects on metabolism:

    • Promotes lipolysis (fat breakdown) and fatty acid oxidation, reducing adiposity.

    • Enhances protein synthesis and nitrogen retention, promoting lean body mass.

    • Reduces glucose uptake in peripheral tissues (anti-insulin effect) while increasing hepatic glucose production.

    • Improves lipid profiles with reduced LDL cholesterol and increased HDL cholesterol.

  • Anabolic Effects: HGH stimulates:

    • Linear growth through epiphyseal plate chondrocyte proliferation.

    • Skeletal muscle hypertrophy through satellite cell activation and protein synthesis.

    • Bone formation through osteoblast proliferation and activity.

    • Organ growth (except the brain) during development.

  • Clinical Research Context: Recombinant human growth hormone (somatropin) has been extensively studied and clinically used for:

    • Growth hormone deficiency in children and adults.

    • Turner syndrome, Prader-Willi syndrome, and chronic renal insufficiency in children.

    • Short stature associated with various conditions.

    • HIV-associated wasting and short bowel syndrome .

    • Anti-aging research: Investigating the potential of GH to counteract age-related decline in muscle mass, bone density, and metabolic function.

  • Aging Research: The age-related decline in GH and IGF-1 levels (somatopause) is associated with:

    • Sarcopenia (age-related muscle loss).

    • Osteoporosis (reduced bone density).

    • Increased adiposity and metabolic dysfunction.

    • Decreased tissue repair and regenerative capacity.

    • Research is actively investigating the potential benefits and risks of GH interventions in aging populations.

  • Neuroprotective Research: GH and IGF-1 have demonstrated neuroprotective properties, including:

    • Promoting neuronal survival and axonal growth.

    • Modulating neuroinflammation .

    • Supporting cognitive function in aging and neurodegenerative models.

  • Focus on Genetic Variability: Research is exploring how genetic polymorphisms in the GH1 gene, growth hormone receptor (GHR) gene, IGF-1 gene, and related signaling pathway genes may influence individual responses to HGH, providing insights for personalized medicine approaches in growth and metabolic disorders.

Important Research Considerations

Handling & Storage:

  • Store refrigerated at 2-8°C. Do not freeze.

  • Protect from light. Keep vials in their original packaging until use.

  • Reconstitute with bacteriostatic water just before use.

  • Use within recommended timeframe after reconstitution (typically 14-28 days when refrigerated).

Purity & Quality:

  • 99.8% purity ensures minimal contaminants and reliable experimental results.

  • Research-grade product is intended for laboratory use only.

Dosing Considerations:

  • Exercise caution with dosing in experimental models due to potent metabolic effects.

  • Monitor glucose levels in relevant studies, as HGH can affect insulin sensitivity.

  • Consider appropriate controls (vehicle-treated, untreated) in experimental design.

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